2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3,3-difluoropropanoic acid - Names and Identifiers
2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3,3-difluoropropanoic acid - Physico-chemical Properties
2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3,3-difluoropropanoic acid - Introduction
N-Fmoc-3,3-Difluoro-DL-alanine(N-Fmoc-3) is an organic compound commonly used for peptide chain synthesis in solid phase synthesis methods.
its nature:
1. molecular formula: C17H14F2NO4
2. molecular weight: 337.29g/mol
3. Appearance: white crystalline powder
4. melting point: 165-170 degrees Celsius
Its purpose:
N-Fmoc-3,3-Difluoro-DL-alanine is mainly used for the synthesis of peptide drugs and peptide fragments. It can be used as a protective group to protect the reactivity of amino acids during synthesis. It can also be used as an amino acid model in drug molecules to study the properties and interactions of amino acids.
its preparation method:
N-Fmoc-3,3-Difluoro-DL-alanine is generally obtained by chemical synthesis. First, fluorenecinol is reacted with 3,3-difluoropropionyl chloride to obtain N-Fmoc-3, 3-difluoropropionyl chloride. N-Fmoc-3, 3-difluoropropionyl chloride is then reacted with alanine to give N-Fmoc-3,3-Difluoro-DL-alanine under basic conditions.
their safety information:
N-Fmoc-3,3-Difluoro-DL-alanine has certain stability and low toxicity under conventional experimental conditions. However, as an organic compound, any chemical should be handled with caution. During use, wear appropriate personal protective equipment to avoid direct contact with skin and eyes. If accidental contact occurs, rinse immediately with plenty of water and seek medical help. During storage, it should be kept in a sealed container, away from fire and oxidizing agents.
Please note that when synthesizing and using chemicals, you must first be familiar with the nature and safety information of the chemicals, and follow correct operating procedures and laboratory safety regulations.
Last Update:2024-04-09 21:01:54